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Biography
John Middleton Clayton (1796–1856) was born in Sussex County, Delaware. He graduated from Yale College, practiced law, and entered politics in 1824, when he was elected to the state legislature. In 1828 he was elected to the U.S. Senate and later served as chief justice of the Delaware Supreme Court. In 1849, President Zachary Taylor appointed Clayton secretary of state.
Clayton was a supporter of U.S. commercial expansion. His key achievement as secretary was the 1850 Clayton-Bulwer Treaty, which pledged cooperation with Great Britain in the building of a future canal through Central America, connecting the Atlantic and Pacific Oceans.
Clayton resigned upon the death of President Taylor in July 1850 and in 1853 was returned by voters of Delaware to the U.S. Senate, where he served until his death.